Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1810 | 1810-30512 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, T215F | Y181C, G190A | K101H, V108I | A98S, V111VIM, I135V, Q207E, K223E, L228R, V245M |
| >1810-30512| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP SGLHKKKSVTILDMGDAYFSVPLDKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRTKIEELREHLLRWGFFTP DKKHQEEPPFRWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, I84V, L90M | L33F, G73T | L10I, I13V, N37D, L63P, C67Y, H69R, K70T, A71V, P79A, L89M |
| >1810-30512| codons 4-99 TLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMDLPGRWKPKMIGGIGGFMKVRQYDQIP IEIYGRTVITTVLVGATPVNVIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |