Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1342 | 1342-30423 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | L100I, K103N | V60I, V118VI, K122E, D177E, I178M, T200A, Q207E, E224D |
| >1342-30423| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEMVIYQYMDDLYVGSDLEIGQHRAKIEELREHLWRWGFYTP DKKHQKDPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, I84V, L90M | L10F, L33F, K43T, T74P | I13V, E34Q, M36MI, L63T, A71V, I72V, T91S, I93L |
| >1342-30423| codons 4-99 TLWQRPFVTVKIGGQLKEALLDTGADDTVFQEINLPGRWTPKLIGGIGGFVKVRQYDQIT IEICGHKVVGPVLVGPTPVNVIGRNLMSQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |