<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2211 2211-30819 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184MV, L210W, T215Y D67DG, K219N Y181C V108I, F227L T39A, K43E, I50M, S68SG, A98S, K101Q, K102R, V118I, K122E, I135IL, E203K, Q207A, H208Y, R211K, K223E, L228R L92V, G93R
>2211-30819| codons 38-247
CAELEEEGKISKMGPENPYNTPVFAIKKKGGTKWRKVVDFRELNKRTQDFWEVQVRIPHP
SGLQRKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVGSDLEIGQHRTKIKELRAYLWKWGFYTP
DNKHQEEPPLRWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, L90M G73T, L89V T4S, L10I, K20I, E35N, M36I, D60E, I62V, L63P, K70T, A71V, I72L P44PL
>2211-30819| codons 4-99
SLWQRPIVTIKIGGQLIEALLDTGADDTVLENINLPGRWKLKIIGGVGGFVKVRQYEQVP
IEICGHTVLTTVLVGPTPVNIIGRNVMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006