Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1982 | 1982-30610 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48LV, I54V, V82A, L90M | F53FL | L10V, K20R, M36I, R41K, K43KR, R57K, I62V, L63P, A71V, I72V, T74S, I93L |
| >1982-30610| codons 4-99 TLWQRPVVTIKIGGQLREALLDTGADDTVLEEINLPGKWRPKMIVGIGGLVKVKQYDQVP IEICGHKVVGSVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, L74V, Y115F, M184V | K70KHNQ | K103N, Y181C | S105T, K122E, D192N, Q197E, R211AG, H221Y |
| >1982-30610| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTQWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKTVTVLDVGDAFFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVGSNLEIGEHRTKIEELRQHLLGWGFTTP DKKYQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |