Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1932 | 1932-30513 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, I84V, L90M | L10F, L33F, Q58QE, T74P | I13V, K14R, E35D, M36I, I62V, L63P, I64V, Q92K |
| >1932-30513| codons 4-99 TLWQRPFVTVRIGGQLKEALLDTGADDTVFEDINLPGRWKPKLIGGIGGFVKVREYDQVP VEICGHKAIGPVLVGPTPVNVIGRNLMTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K219KR | K103N | A98G | K43N, E53D, V118VI, K122E, D123N, I142T, T200L, H208Y |
| >1932-30513| codons 38-247 CTELENEGKISKIGPDNPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRLKIEELRQYLWRWGFYTP DRKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |