Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1930 | 1930-30507 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54V, V82A | L24I, L33LF | L10I, T12P, I13IV, K14R, K20R, E35D, M36I, N37E, K55KR, R57K, L63P, A71T, T74S, V77VI, I93L |
| >1930-30507| codons 4-99 TLWQRPIVPVRIGGQLREALIDTGADDTVFEDIELPGRWKPKIIGGIGGFVRVKQYDQIP IEICGHKTIGSVLIGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, K70R, M184V, T215F | D67G, T69G, K219E | G190A | K43EQ, V60VI, A98S, K101Q, K122E, I135L, S162C, D177DG, V179I |
| >1930-30507| codons 38-247 CTELEQEGKISKIGPENPYNTPIFAIKKKGSGRWRKLVDFRELNKRTQDFWEVQLGIPHP SGLQKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPGIIIYQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTP DEKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |