<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1079 1079-30408 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, V75M, M184V, L210W, T215Y K219N K101E, Y181C, G190A V108I K43E, E44A, W88C, V118I, K122E, D123DN, Q174K, I178L, I195IT, G196GE, T200TA, E203K, Q207E, H208Y, R211K, H221Y  
>1079-30408| codons 38-247
CTELEEAGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKRTQDFCEVQLGIPHP
AGLEKKKSVTILDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKKNPDLVICQYVDDLYVASDLETEQHRAKIKELREYLWKWGFYTP
DNKYQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I84V, L90M L33F L10I, I13V, K14KR, N37ND, L63P, A71V, I72ILM, V77I, Q92K, I93L G73N
>1079-30408| codons 4-99
TLWQRPIVTVRIGGQLKEALLDTGADDTIFEEMDLPGRWKPKIVGGIGGFIKVRQYDQIP
IEICGHKVMNTVLIGPTPVNVIGRNLMTKLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006