<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1739 1739-30417 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I50V, I54V, V82A, L90M V11I, L33F, K43T, F53L, L89V L10IV, I13V, K20R, E35D, M36I, R41K, K55R, D60E, I62V, L63P, I64M, A71I, Q92R, I93L, C95F  
>1739-30417| codons 4-99
TLWQRPVITVKIGGQLREALLDTGADDTVFEDINLPGKWTPKLIGGVGGLVRVRQYEQVP
MEICGHKIIGTVLVGPTPANIIGRNVMTRLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F, Q151M, L210W A62V, V75I, F77L, F116Y K101E, Y181C, G190A V179F T58N, S68G, T69I, K102Q, K103R, K122E, S162C, R172K, Q174K, R211AT  
>1739-30417| codons 38-247
CTEMEKEGKISKIGPENPYNNPVFVIKRKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLEQRKSVTVLDVGDAFYSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQCSMTKILEPFKKKNPDIFICQYMDDLYVASDLEIGQHRTKIEELRQHLWTWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006