Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1832 | 1832-30623 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, V75T, M184V, T215Y | A62V | T39TIM, K43E, E44A, K49R, S68G, V90I, V118I, D123E, I135T, S162D, D177E, V179VI, G196E, T200A, Q207D, L210F, R211K, V245T |
| >1832-30623| codons 38-247 CMELEEAGKISRIGPENPYNTPVFVIKKKDGTKWRKITDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFRKQNPEIIIYQYVDDLYVGSDLEIEQHRAKIEELRDHLFKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, G48V, I54S, V82A | L33F, G73S | L10I, I13V, I15V, L63P, A71V, I72M, V77VI, I93L |
| >1832-30623| codons 4-99 TLWQRPIVTVKVGGQLKEALLDTGADDTVFEEMNLPGRWKPKIIVGIGGFSKVRQYDQIP IEICGHKVMSTVLIGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |