Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1660 | 1660-30528 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, T215F | K219Q | Y181C, G190A | V60I, K102N, V118I, K122E, I135T, S162D, V179I, T200IR, Q207E, R211RK, F214L, D218E, L228H, V245E |
| >1660-30528| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKNKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFRKQNPDIIICQYVDDLYVASDLEIGQHRRKIEELREHLLKWGLFTP EQKHQKEPPFHWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, V82C, I84V, L90M | L10F, V11I, F53L, G73A, L89V | I13V, I15V, G16A, K20I, K55R, R57K, L63P, T74S, P79A |
| >1660-30528| codons 4-99 TLWQRPFITVKVAGQLIEALLDTGADDTVLEEMNLPGRWKPKIVGGIGGLVRVKQYDQIP IEICGHKAIASVLVGATPCNVIGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |