Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1655 | 1655-30528 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184MV, L210W, T215Y | K103KN | A98G | E44D, V60I, K102KR, V118I, K122E, I135T, S162C, G196E, R211K, V245VE |
| >1655-30528| codons 38-247 CTELEKDGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLKRNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82F, L90M | G48E, F53FL | L10I, G17E, K20T, M36MI, I62V, L63P, A71V, V77I, I85V, I93L |
| >1655-30528| codons 4-99 TLWQRPIVTIKIGEQLTEALLDTGADDTVLEEINLPGRWKPKLIEGIGGLVKVRQYDQVP IEICGHKVIGTVLIGPTPFNIVGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |