Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1064 | 1064-30522 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MIL, I54ILM, I84V, L90M | V11VI, L33F, G73C | L10I, I13V, M36ML, R41K, K55KR, I62IV, L63P, A71T, I72R, V77I, I93L |
| >1064-30522| codons 4-99 TLWQRPIITVKIGGQLKEALLDTGADDTVFEELNLPGKWKPKLIGGIGGFMRVRQYDQVP IEICGHKTRCTVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215F | K219Q | V60I, T69N, K122E, D123N, I135T, S162SDGN, D177E, I178IM, V179VI, G196E, T200A, Q207E, H208HY, D218E, L228H |
| >1064-30522| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPEMIIYQYVDDLYVGSDLEIEQHRAKIEELREYLLRWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |