Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1060 | 1060-30429 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, L90M | L33F, Q58E, G73S | I13V, I15V, K20T, E35D, M36I, N37ND, I62V, L63P, K70E, A71V, V77VI, I93L |
| >1060-30429| codons 4-99 TLWQRPLVTVKVGGQLTEALLDTGADDTVFEDIDLPGRWKPKLIGGIGGFIKVREYDQVP IEICGHEVISTVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219N | K43E, E44A, R83K, K102Q, V118I, K122E, D177E, I178L, I202V, Q207E |
| >1060-30429| codons 38-247 CTELEEAGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKKTQDFWEVQLGIPHP AGLKQKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPELVIYQYVDDLYVGSDLEIGQHRTKVEELREHLWRWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |