<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2267 2267-30820 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, Y115F, Q151M, M184V, T215FL V75I, F77L, F116Y, K219Q Y181C, G190A V108I K49R, K101Q, V118I, K122E, S162ST, T165I, Q174R, V179I, G196E, T200A, E203D, F214L, H221Y, L228H  
>2267-30820| codons 38-247
CTEMEKEGKISRIGPENPYNTPVFAIKKKNSDKWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLQKKKSVTILDVGDAFYSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQTSMIKILEPFRKRNPDIIICQYVDDLYVASDLEIEQHRAKIDELRQHLLRWGLLTP
DQKYQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, L90M F53L, G73A, L89V L10I, I13V, L19P, K20V, A22AV, E35G, M36I, D60E, I62V, L63P, I64V, A71I, I72T, V77I, V82I, I85V  
>2267-30820| codons 4-99
TLWQRPIVTVKIGGQPVEVLLDTGADDTILEGINLPGRWKPKIVGGIGGLMKVRQYEQVP
VEICGHKITATVLIGPTPINIVGRNVMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006