<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2165 2165-30821 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y K219R K103N A98G, K238T T39E, E44D, V60I, I94L, V111I, V118I, K122E, D123N, I135L, E138A, M164L, K166R, V189VI, G196E, T200A, E203D, H208Y, R211K K173KHNQ
>2165-30821| codons 38-247
CEELEKDGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGLPHP
GGLKKNKSVTVLDIGDAYFSIPLDENFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSP
AIFQSSLTRILEPFRQQNPDIVIYQYVDDLYIGSDLEIEQHRAKIDELRQYLWKWGFYTP
DRKHQKEPPFLWMGYELHPDTWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54T, V82A K43KT L10I, L19LI, K20R, E35D, M36I, N37D, L63P, A71I, I72V, I93M  
>2165-30821| codons 4-99
TLWQRPIVTIKIGGQIREALLDTGADDTVLEDIDLPGRWTPKMIVGIGGFTKVRQYDQIP
IEICGHKIVGTVLVGPTPANIIGRNLLTQMGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006