<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1018 1018-30520 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y V75M K103N A98G, V108I K43KN, E44D, V118I, K122E, S162C, E169D, N175H, V189I, T200A, K201M, E203D, H208Y, R211K, H221Y  
>1018-30520| codons 38-247
CTELENDGKISKIGPENPYNTPVFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHP
GGLKKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILDPFRKQHPDIVIYQYVDDLYIGSDLEIGQHRAMIDELRQYLWKWGFYTP
DKKYQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L24I, L33F, K43IT, G73C L10I, I15V, L19LI, M36L, N37S, L38W, P39PS, R41RK, I62V, L63P, A71V  
>1018-30520| codons 4-99
TLWQRPIVTIKVGGQIKEALIDTGADDTVFEELSWSGKWTPKLIGGIGGFVKVRQYDQVP
IEICGHKVICTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006