Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2030 | 2030-30724 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | T69H, V90I, K122E, I135T, H208HY, R211K, E224ED, K238R |
| >2030-30724| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSHRWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQYLLKWGFFTP DQKHQKDPPFLWMGYELHPDRWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V, L90LM | L33F, Q58E | L10IV, I13V, K20R, E35D, M36I, R41K, D60E, I64V |
| >2030-30724| codons 4-99 TLWQRPVVTVKIGGQLREALLDTGADDTVFEDINLPGKWKPKMIGGIGGFVKVREYEQIL VEICGHKAIGTVLVGPTPANVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |