<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2027 2027-30722 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, L74I, M184V, T215F K219Q   A98G T39A, I94L, V118I, K122E, Q174N, I202V, R211RT, F214L, D218E, L228H, Q242H, V245M  
>2027-30722| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKIVDFRELNKRTQDFWEVQLGLPHP
GGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKNNPDIVIYQYVDDLYVGSDLEIGQHRTKVEELRQHLLTWGLFTP
EQKHQKEPPFHWMGYELHPDKWTVHPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I54V, V82A, L90M V11I, K43T, F53L, L89V L10V, I13V, K20V, M36I, Q61H, L63P, A71I, Q92K  
>2027-30722| codons 4-99
TLWQRPVITVKIGGQLVEALLDTGADDTILEEINLPGRWTPKIIGGIGGLVKVRQYDHIP
IEICGHKIIGTVLVGPTPANIIGRNVMTKIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006