Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1324 | 1324-30501 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54IL, V82A, L90M | L33F, F53FL | L10V, I13V, G16GA, K20T, L63P, A71V |
| >1324-30501| codons 4-99 TLWQRPVVTVKIAGQLTEALLDTGADDTIFEEMNLPGRWKPKIVGGIGGLLKVRQYDQIP IEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67N, K70R, T215F | K219E | K103N, Y181C | K66KR, V90I, K101KQ, K122E, I135T, S162Y, G196E, L228R, D237E |
| >1324-30501| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKRNSTRWRKLVDFRELNKRTQDFWEIQLGIPHP AGLQKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGFFTP DEKHQKEPPFRWMGYELHPEKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |