Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1531 | 1531-30820 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K219N | L100I, K103N | T39A, K43Q, V60I, V118I, K122E, G196E, I202V, R211K |
| >1531-30820| codons 38-247 CAELEQEGKISKIGPENPYNTPIFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRTKVEELRQHLWKWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10I, K20R, E35D, M36I, R41K, I62V, L63P, A71I, I93L |
| >1531-30820| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYDQVP IEICGHKIIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |