Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2151 | 2151-30623 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, L210W, T215Y | V75L, F77L, K219E | K101E, Y181C, G190A | F227FL | K122E, I135T, I167IV, V179I, D218E, L228H |
| >2151-30623| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLLDLRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKVLEPFRKQNPDIIICQYVDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTP EEKHQKEPPLHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54A, V82A | L10F, K43KT | I13V, Q18H, K20M, M36I, N37D, R41K, I62V, L63P, I64V, T74S, L89I |
| >2151-30623| codons 4-99 TLWQRPFVTVKIGGHLMEALLDTGADDTVLEEIDLPGKWTPKLIGGIGGFAKVRQYDQVP VEICGHKAIGSVLVGPTPANIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |