Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1783 | 1783-30515 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69A_VA, M184V, L210W | A62V, T215C | Y188L | K43Q, I94L, V106I, V118I, K122E, D123DN, Q174R, I202IV, R211K, F214L |
| >1783-30515| codons 38-247 CTELEQEGKISKIGPENPYNTPVFVIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGLPHP AGLKKKKSITVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPDIVIYQYVDDLLVGSDLEIGQHRTKVEELRQHLWKWGLCTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, I84V, L90M | L10F, V11I, Q58E, G73S, L89V | I15V, K20V, E35D, M36I, N37E, R57RK, I62V, L63P, K70R, A71V, I72L, I85V |
| >1783-30515| codons 4-99 TLWQRPFITIKVGGQLVEALLDTGADDTVLEDIELPGRWKPKIIGGIGGFVKVKEYDQVP IEICGHRVLSTVVVGPTPVNVVGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |