<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1053 1053-30402 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, L210W, T215F K219Q Y181C   T39E, V60VI, T69N, K102Q, I132IV, I135IV, Q174K, D177N, G196E, I202V, E203K, Q207E, H208HY, R211RK, D218E, L228H  
>1053-30402| codons 38-247
CEEMEKEGKISKIGPENPYNTPIFAIKKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTVPSVNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKKNPNIVICQYMDDLYVGSDLEIEQHRTKVKELREYLWKWGFFTP
EQKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, I84V, L90M L33F, G73T L10I, K20R, L24F, E35D, M36I, N37D, K43Q, I62V, L63P, I64V, A71V, I72R, P79A  
>1053-30402| codons 4-99
TLWQRPIVTIKIGGQLREALFDTGADDTVFEDIDLPGRWQPKLIGGIGGFVKVRQYDQVP
VEICGHKVRTTVLVGATPVNVIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006