Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1041 | 1041-30717 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69G_SG, M184V, L210W, T215CY | K70A, V75L | L100LI, K103N | K238T | T39A, S48E, S162A, Q174R, R211K, K223KR, L228H | K154KQ, K201KE |
| >1041-30717| codons 38-247 CAELEKEGKIEKIGPENPYNTPVFAIKKKDSGAWRKLLDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWQGSP AIFQASMTKILEPFRKRNPDIVIYQYVDDLYVGSDLEIGQHRTEIEELRQHLWKWGFYTP DKKHQREPPFHWMGYELHPDTWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, I84V | V11I, L24I | L10I, I15V, L19P, K20V, A22V, K55KR, I62IV, L63P, A71V, I72V, T74S, T91S |
| >1041-30717| codons 4-99 TLWQRPIITIKVGGQPVEVLIDTGADDTVLEEMNLPGRWKPKLIGGIGGFVRVRQYDQVP IEICGHKVVGSVLVGPTPANVIGRNLLSQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |