Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1038 | 1038-30609 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, L210W, T215Y | L100I, K103N | K43Q, V60I, V118I, K122P, I142M, T200A, E204Q, Q207D, R211K | A98E |
| >1038-30609| codons 38-247 CTELEQEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP EGIKKNKSVTVLDVGDAYFSIPLDPDFRKYTAFTIPSINNETPGMRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEQLRDHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, V82VA, I84IV | L19Q, K20R, E21*, E35D, R57K, I62IV, L63P, A71T, I72V, V77I |
| >1038-30609| codons 4-99 TLWQRPLVTIKIGGQQR*ALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFVKVKQYDQVP IEICGHKTVGTVLIGPTPANVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |