Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1032 | 1032-30313 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IV, I84V, L90M | G73S | L10I, L63P, A71V, V77VI, I93L |
| >1032-30313| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYDQIP IEICGHKVISTVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, V75M, M184MV, L210W, T215Y | K219R | Y181C | A98G, V108I | E40F, K43E, R83K, V106I, V118I, D121H, K122E, D177E, V189VI, D192DY, T200I, E203K, Q207D, H208Y, R211K, K223E, L228R |
| >1032-30313| codons 38-247 CTFLEEEGKISKIGPENPYNTPVFAIKKKDSDKWRKLMDFRELNKKTQDFWEVQLGIPHP GGLKKKKSITILDVGDAYFSIPLHEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVICQYVDDLYIGSYLEIGQHRIKIKELRDYLWKWGFYTP DRKHQEEPPFRWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |