<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1706 1706-30410 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y     V108I T39TAEK, K43E, E44D, E53ED, K64R, A98S, K101Q, V118I, K122E, D123N, I135T, T200TAEK, E203K, Q207D, H208Y, R211K, K223Q  
>1706-30410| codons 38-247
CKELEEDGKISKIGPDNPYNTPVFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
SGLQKKKSVTILDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRKKIKELRDYLWKWGFYTP
DKKHQQEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54L, I84V, L90M V11VI, L33LF, F53L, G73T L10I, T12AP, I13V, G16A, D60E, L63P, I64V, A71V, I72IT, V77VI, I93IL  
>1706-30410| codons 4-99
TLWQRPIIPVKIAGQLKEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGLLKVRQYEQIP
VEICGHKVTTTVLIGPTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006