<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1028 1028-30325 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, V75M, L210W, T215Y K219D K103N   T39AV, V60I, K82R, A98S, V118I, K122E, I135T, S162H, D177N, G196E, H208F, R211N, L228LH  
>1028-30325| codons 38-247
CVELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLMDFRELNRRTQDFWEVQLGIPHP
SGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQHSMTKILEPFRKQNPNIVIYQYMDDLYVGSDLEIEQHRTKIEELRQFLWNWGFYTP
DDKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, I84V, L90M V11I, L33F, G73GCFV, T74P, L89AV L10I, T12P, G16A, K20IV, E34EA, M36MI, R41K, Q61D, I62V, L63P, C67Y, A71V, I72L, V77I, I93L  
>1028-30325| codons 4-99
TLWQRPIIPIKIAGQLVEALLDTGADDTIFAEINLPGKWKPKIVGGIGGFMKVRQYDDVP
IEIYGHKVLVPVLIGPTPVNVIGRNVMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006