Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1901 | 1901-30605 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, L210W, T215Y | V75S, K219N | K103S, Y181C, G190GA | V108VIL | T39A, K43Q, V118I, K122E, D123DN, S162SN, D192DN, G196E, T200A, R211K, D218E, L228HR, Q242L, V245VM |
| >1901-30605| codons 38-247 CAELEQEGKISKIGPENPYNTPVFAIKKKDSTKWRKISDFRELNKRTQDFWEVQLGIPHP AGLKKSKSVTLLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPDIVICQYVDDLYVASNLEIEQHRAKIEELRQHLWKWGFYTP ENKHQKEPPFRWMGYELHPDKWTVLPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54A, V82A, L90M | L33F, G73T | L10I, G16GA, E34Q, D60E, I62V, L63P, C67F, A71L, I72E, V77I, I93L |
| >1901-30605| codons 4-99 TLWQRPIVTIKIAGQLKEALLDTGADDTVFQEMNLPGRWKPKMIGGIGGFAKVRQYEQVP IEIFGHKLETTVLIGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |