<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1901 1901-30605 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54A, V82A, L90M L33F, G73T L10I, G16GA, E34Q, D60E, I62V, L63P, C67F, A71L, I72E, V77I, I93L  
>1901-30605| codons 4-99
TLWQRPIVTIKIAGQLKEALLDTGADDTVFQEMNLPGRWKPKMIGGIGGFAKVRQYEQVP
IEIFGHKLETTVLIGPTPANIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, L210W, T215Y V75S, K219N K103S, Y181C, G190GA V108VIL T39A, K43Q, V118I, K122E, D123DN, S162SN, D192DN, G196E, T200A, R211K, D218E, L228HR, Q242L, V245VM  
>1901-30605| codons 38-247
CAELEQEGKISKIGPENPYNTPVFAIKKKDSTKWRKISDFRELNKRTQDFWEVQLGIPHP
AGLKKSKSVTLLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQNSMTKILEPFRKQNPDIVICQYVDDLYVASNLEIEQHRAKIEELRQHLWKWGFYTP
ENKHQKEPPFRWMGYELHPDKWTVLPIMLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006