<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2083 2083-30609 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, M184V, L210W, T215Y K219N K101E, Y181V   T39A, E40V, K43E, V118I, K122P, S162C, S163G, I178IM, V179I, R211K, D218E  
>2083-30609| codons 38-247
CAVLEEEGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTVLDVGDAYFSIPLDPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQCGMTKILEPFRKQNPDMIIVQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTP
ENKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, L90M G73S L10I, T12E, I13V, K20I, M36I, K55R, I62V, L63P, C67F, A71V, I72M  
>2083-30609| codons 4-99
TLWQRPIVEVKIGGQLIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVRVRQYDQVP
IEIFGHKVMSTVLVGPTPTNIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006