<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2010 2010-30606 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, L74LV, Y115YF, M184MV, T215F K219Q Y181YC   T39E, K49R, V60I, V90I, A98S, K122E, D123E, P170PS, D218E, L228LH, I244IV S162DE
>2010-30606| codons 38-247
CEELEKEGKISRIGPENPYNTPIFAIKKKNSTRWRKVVDFRELNKRTQDFWEIQLGIPHP
SGLKKKKSVTVLDVGDAFFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQESMTKILESFRKQNPDIVICQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFFTP
EQKHQKEPPFHWMGYELHPDKWTVQPVVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I50V, V82A, L90M V11I, L33F, M46V, F53L L10I, I13V, L19I, K20R, E35D, M36I, N37D, K55R, R57K, L63P, A71V  
>2010-30606| codons 4-99
TLWQRPIITVKIGGQIREALLDTGADDTVFEDIDLPGRWKPKVIGGVGGLIRVKQYDQIP
IEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006