Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2009 | 2009-30606 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, I54L, V82F, L90M | L33F, K43T | L10I, V11F, I13V, K20R, E35D, M36I, N37D, D60E, I62V, L63PT, A71I, V77I, I93L |
| >2009-30606| codons 4-99 TLWQRPIFTVKIGGQLREALLDTGADDTIFEDIDLPGRWTPKMVGGIGGFLKVRQYEQVT IEICGHKIIGTVLIGPTPFNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T215Y | K219N | Y188L | T39A, K43E, E44A, K102M, V106I, S117A, T139A, I178IM, V179I, I202IV, Q207D, H208Y, R211K, W212L, D218E, H221Y, L228K |
| >2009-30606| codons 38-247 CAELEEAGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKMKKSITVLDVGDAYFAVPLDKDFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMIIYQYMDDLLVGSDLEIGQHRTKVEELRDYLLKLGFYTP ENKYQKEPPFKWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |