Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2006 | 2006-30604 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, I84V | L24I, L33F | Q7E, L10I, T12K, I13IV, L19I, K20T, K43KI, L63P, I64IV, A71V, T91S, Q92R |
| >2006-30604| codons 4-99 TLWERPIVKVKIGGQITEALIDTGADDTVFEEMNLPGRWIPKIIGGIGGFVKVRQYDQIP VEICGHKVIGTVLVGPTPTNVIGRNLLSRIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K103N | A98GS | T39K, K43E, E44D, V60I, K101KQ, V118I, K122E, D123E, I135T, Q174QR, G196E, I202V |
| >2006-30604| codons 38-247 CKELEEDGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLQKNKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPDIVIYQYVDDLYVGSDLEIEQHRTKVEELRQHLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |