<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2007 2007-30604 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, M184V, L210W, T215Y K219N Y181C, G190A K101H T39A, E40F, K43E, K122E, I167V, T200E, E203K, H208Y, R211K, K223E, L228R, V241I, V245K S117S*, N147NH, P226PS
>2007-30604| codons 38-247
CAFLEEEGKISKIGPENPYNTPVFAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLHKKKSVTVLDVGDAYF*VPLDEDFRKYTAFTIPSINNETPGIRYQYHVLPQGWKGSP
AIFQSSMTKVLEPFRKQNPDIVICQYVDDLYVASDLEIGQHREKIKELRQYLWKWGFYTP
DNKHQEEPSFRWMGYELHPDKWTIQPIKLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I54V, L90M L23I, L33LI, M46V, F53L, Q58E, G73S L10I, I13IV, K20R, E35D, M36I, N37S, R57K, I62IV, L63P, I64V, A71V, V82I  
>2007-30604| codons 4-99
TLWQRPIVTVKIGGQLREAILDTGADDTIIEDISLPGRWKPKVIGGIGGLVKVKEYDQVP
VEICGHKVISTVLVGPTPINIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006