Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2007 | 2007-30604 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I54V, L90M | L23I, L33LI, M46V, F53L, Q58E, G73S | L10I, I13IV, K20R, E35D, M36I, N37S, R57K, I62IV, L63P, I64V, A71V, V82I |
| >2007-30604| codons 4-99 TLWQRPIVTVKIGGQLREAILDTGADDTIIEDISLPGRWKPKVIGGIGGLVKVKEYDQVP VEICGHKVISTVLVGPTPINIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, M184V, L210W, T215Y | K219N | Y181C, G190A | K101H | T39A, E40F, K43E, K122E, I167V, T200E, E203K, H208Y, R211K, K223E, L228R, V241I, V245K | S117S*, N147NH, P226PS |
| >2007-30604| codons 38-247 CAFLEEEGKISKIGPENPYNTPVFAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLHKKKSVTVLDVGDAYF*VPLDEDFRKYTAFTIPSINNETPGIRYQYHVLPQGWKGSP AIFQSSMTKVLEPFRKQNPDIVICQYVDDLYVASDLEIGQHREKIKELRQYLWKWGFYTP DNKHQEEPSFRWMGYELHPDKWTIQPIKLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |