<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1962 1962-30523 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N L100I, K103N   T39K, K43E, E44A, K64R, V118I, K122E, I142V, D177N, T200A, H208Y, R211K, D218E, F227Y, L228H  
>1962-30523| codons 38-247
CKELEEAGKISKIGPENPYNTPVFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPNIVIYQYVDDLYVGSDLEIGQHRAKIEELRQYLWKWGFYTP
ENKHQKEPPYHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54M, I84V, L90M L10F, L33F, K43T, G73T E34Q, N37S, R41K, D60DE, I62V, L63P, I66V, C67F, A71T, I72T, V77I, I93L  
>1962-30523| codons 4-99
TLWQRPFVTIKIGGQLKEALLDTGADDTVFQEMSLPGKWTPKIIGGIGGFMKVRQYEQVP
IEVFGHKTTTTVLIGPTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006