<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1013 1013-30228 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, L74LI, M184V, L210W   Y181C, G190GA A98G, V179DY E40F, K43Q, R83K, K103R, V106VI, L109LIM, I135L, S163SC, I167V, T200A, Q207E, R211K, L228R, D237E, V245E  
>1013-30228| codons 38-247
CTFLEQEGKISKIGPENPYNTPVFAIKKKDSDKWRKIVDFRELNKKTQDFWEVQLGIPHP
GGLKKRKSITVMDVGDAYFSVPLDKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP
AIFQSCMTKVLEPFRKQNPDIYICQYVDDLYVASDLEIGQHRAKIEELREHLWKWGFTTP
DKKHQKEPPFRWMGYELHPEKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82C, I84V L10F, L24I, L33F, K43T I13V, G16A, Y59YF, Q61R, L63P, I64V, K70KR, A71V, I72E, T74S, V77I, P79Q, T91S, I93L  
>1013-30228| codons 4-99
TLWQRPFVTVKIAGQLKEALIDTGADDTVFEEMNLPGRWTPKLIGGIGGFVKVRQFDRIP
VEICGHRVEGSVLIGQTPCNVIGRNLLSQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006