<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1308 1308-30408 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, V75T, Y115YF, M184V, L210W, T215Y K219KR Y188L Y181YF K43Q, I94IL, V118I, D123E, K166R, D177E, V189VI, T200A, E203D, Q207E, H208HY, R211K, D218E, L228H, Q242H, V245Q  
>1308-30408| codons 38-247
CTELEQEGKISKIGPENPYNTPVFAIKKKDSTKWRKITDFRELNKRTQDFWEVQLGLPHP
AGLKKKKSVTVLDVGDAFFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRKQNPEIVIFQYVDDLLIGSDLEIGQHRAKIDELREYLWKWGFYTP
ERKHQKEPPFHWMGYELHPDKWTVHPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, G48V, I54T, V82A L24LI, L33F, K43T L10I, I13V, K20R, E35D, M36I, N37D, I62V, L63Q, I72V, T74S, I85V, L89M  
>1308-30408| codons 4-99
TLWQRPIVTVKIGGQLREALIDTGADDTVFEDIDLPGRWTPKLIVGIGGFTKVRQYDQVQ
IEICGHKAVGSVLVGPTPANIVGRNMLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006