Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1304 | 1304-30717 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46ML, I54L, L90M | L10F, L33F, Q58E, N88D | I13IV, G16GA, E35ED, N37S, I62V, L63P, I72IM, V77VI, I93L |
| >1304-30717| codons 4-99 TLWQRPFVTVKIAGQLKEALLDTGADNTVFEDMSLPGRWKPKLIGGIGGFLKVREYDQVP IEICGHKAMGTVLIGPTPVNIIGRDLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219Q | K103N | V60I, K122E, I135T, S162Y, K173KQ, Q207DE, R211RK, F214L, L228H |
| >1304-30717| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRQQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |