Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1302 | 1302-30711 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, Q58E, G73S, L89V | I13V, K20T, L33V, K55R, D60E, Q61DE, I64V, T91TS |
| >1302-30711| codons 4-99 TLWQRPFVTVKIGGQLTEALLDTGADDTVVEEMNLPGRWKPKIIGGIGGFVRVREYEEIL VEICGHKAISTVLVGPTPVNVIGRNVMSQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69TADN, L210W, T215Y | K219R | K103KN | K43E, V118I, G196E, T200A, Q207E, H208Y, R211K, L228H, V245E |
| >1302-30711| codons 38-247 CTELEEEGKISKIGPENPYNTPVFAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELREYLWKWGFYTP DRKHQKEPPFHWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |