Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1771 | 1771-30529 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, L90M | L10I, I13V, E35D, M36I, N37D, L63P, I72V, V82VI, Q92QK |
| >1771-30529| codons 4-99 TLWQRPIVTVKIGGQLKEALLDTGADDTILEDIDLPGRWKPKMVGGIGGFIKVRQYDQIP IEICGHKAVGTVLVGPTPINIIGRNLMTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215Y | V75AS, K219E | G190Q | V179D | E44D, V60VI, V118I, K122E, H208Y, L210Y, R211K, D218E, L228H |
| >1771-30529| codons 38-247 CTELEKDGKISKIGPENPYNTPIFAIKKKNSTRWRKISDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIDIYQYVDDLYVQSDLEIGQHRTKIEELRQYLYKWGFYTP EEKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |