Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2413 | 2413-30815 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S_VG, V75M, M184V | K103N | V108I, K238T | K46Q, K64R, S117T, V118I, K122E, I135T, V189VI, F214L, H221Y, L228R |
| >2413-30815| codons 38-247 CTEMEKEGQISKIGPENPYNTPVFAIRKKDSSKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTILDVGDAYFTIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYIGSDLEIGQHRTKIEELRQHLLRWGLTTP DKKYQKEPPFRWMGYELHPDTWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A, L90M | V11I, G73S | L10I, T12P, I13V, I15V, K20I, M36I, N37S, I62V, L63P, C67CY, G68E, A71V, I72L |
| >2413-30815| codons 4-99 TLWQRPIIPVKVGGQLIEALLDTGADDTVLEEISLPGRWKPKMIVGIGGFVKVRQYDQVP IEIYEHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |