<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1475 1475-30723 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V, L90M L10F, D30Y, L33F, Q58E, T74P I13V, I62V, L63P, A71V, V77I, P79D, I93L  
>1475-30723| codons 4-99
TLWQRPFVTVKIGGQLKEALLDTGADYTVFEEMNLPGRWKPKIIGGIGGFIKVREYDQVP
IEICGHKVIGPVLIGDTPVNVIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, L74V, M184V, T215F K219Q L100I, K103N   T39A, K43Q, E44A, V60I, T69H, S117SA, K122E, D123E, S162SDGN, K166R, I167IV, D177DG, V179I, G196E, T200E, I202V, E203K, H208Y, R211K, D218E, E224D, L228H, K238R, Q242H F61FC, Q197A
>1475-30723| codons 38-247
CAELEQAGKISKIGPENPYNTPICAIKKKDSHRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGIKKNKSVTVLDVGDAYFAVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQNSMTRVLEPFRKQNPGIIIYQYVDDLYVGSDLEIEAHREKVKELRQYLLKWGFFTP
EQKHQKDPPFHWMGYELHPDRWTVHPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006