<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-4008 4008-30129 Australia 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, K70KR, Q151LM, M184MV, T215TFIS A62AV, V75VI, F77FL, F116FY Y188L   S68SG, T69TN, K101R, K122E, E138A, T139TA, I142T, S162SC, T165TI, I178IM, V179VI, I202IV, Q207D, R211K  
>4008-30129| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFVIKRKDGNRWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLRKKKSVTVLDVGDAYYSVPLDEDFRKYTAFTIPSINNAAPGTRYQYNVLPMGWKGSP
AIFQCSMIKILEPFRKQNPDMIIYQYVDDLLVGSDLEIGQHRTKVEELRDHLLKWGFSTP
DKKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, M36I, L63T, I64V  
>4008-30129| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQIT
VEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006