Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-4069 | 4069-30225 | Australia | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, M46I, I47IV, I54IV, I84V, L90M | L10FI, V11I, L33F, G73T | L63P, A71V, I72IT, V77I, I93L |
| >4069-30225| codons 4-99 TLWQRPIITIKIGGQLKEALLDTGADDTIFEEMNLPGRWKPKIVGGIGGFVKVRQYDQIP IEICGHKVTTTVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219R | K101E, G190GS | K43E, E44A, V60VI, V118I, K122E, E138EQ, K166R, V179VI, R211K |
| >4069-30225| codons 38-247 CTELEEAGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNQTPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIIIYQYMDDLYVSSDLEIGQHRTKIEELRQHLWKWGFYTP DRKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |