<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-3064 3064-30327 Canada 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, L210LW, T215FY K219E K103KN   T39TA, E40FV, K43N, V60I, T69N, V118VI, D121Y, K122E, I142IV, D177E, I178IM, V179I, G196E, T200TA, H208HY, R211RK, L228H, Q242QH  
>3064-30327| codons 38-247
CAVLENEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSIPLYEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEMIIYQYVDDLYVGSDLEIEQHRAKIEELRQYLWKWGFYTP
DEKHQKEPPFHWMGYELHPDKWTVHPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54IMV, V82A, L90M K43T, F53L L10I, G16E, L19LI, K20KR, M36MI, D60E, L63P, I64IV, A71IT, I93L  
>3064-30327| codons 4-99
TLWQRPIVTIKIEGQIREALLDTGADDTILEEINLPGRWTPKIVGGIGGLVKVRQYEQIP
VEICGHKTIGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006