Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-3043 | 3043-30320 | Canada | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215F | K219Q | K103N, Y181C | K122E, K173R, I202V, R211K, L228HR | H235HR |
| >3043-30320| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRRQNPDIVICQYVDDLYVGSDLEIGQHRTKVEELRQHLWKWGFFTP DQKHQKEPPFRWMGYELRPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48A, I54V, V82A, I84V, L90M | K43T | L10I, I15V, K20R, E35D, M36I, N37D, L63P, I64V, I85V |
| >3043-30320| codons 4-99 TLWQRPIVTIKVGGQLREALLDTGADDTVLEDIDLPGRWTPKLIAGIGGFVKVRQYDQIP VEICGHKAIGTVLVGPTPANVVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |