<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-3056 3056-30403 Canada 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M, M184V A62V, V75I, F77FL, F116Y Y181YC, Y188L   T39A, S68G, V118I, K122E, I135T, I142V, V179I, V189VI, G196E, T200A, I202V, H208HY, F214L, D237E T69IV, K102LM
>3056-30403| codons 38-247
CAEMEKEGKISKIGPENPYNTPVFVIKRKDGVKWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLKMKKSVTVLDVGDAYYSIPLDEDFRKYTAFTIPSTNNETPGVRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRKQNPDIIICQYVDDLLIGSDLEIEQHRAKVEELRQYLLRWGLTTP
DKKHQKEPPFLWMGYELHPEKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L10F, V11I, L33F, Q58E, G73T T12E, K14R, E34Q, D60DN, I62V, L63P, A71V, I72T, V77I, P79D, T91S, I93L  
>3056-30403| codons 4-99
TLWQRPFIEIRIGGQLKEALLDTGADDTVFQEMNLPGRWKPKIIGGIGGFVKVREYNQVP
IEICGHKVTTTVLIGDTPVNVIGRNLMSQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006