Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2192 | 2192-30822 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215F | K219Q | K103N | A98G | V60I, T69N, K122E, S162SN, I167IV, I178IM, G196E, I202IV |
| >2192-30822| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQNSMTKVLEPFRKQNPDMVIYQYVDDLYVGSDLEIEQHRTKVEELRQHLLRWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | L10F, V11I, G73T | T4S, T12K, I15V, L19P, K20I, A22V, M36I, I62V, L63P, I64IV, C67F, H69R, A71V, N83S, I85V, T91S |
| >2192-30822| codons 4-99 SLWQRPFIKIKVGGQPIEVLLDTGADDTVLEEINLPGRWKPKMIGGIGGFVKVRQYDQVP VEIFGRKVITTVLVGPTPVSVVGRNLMSQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |